Hormonal

Low baseline ribosome-related gene expression and resistance training-induced declines in ribosome-related gene expression are associated with greater skeletal muscle hypertrophy in young men and women.

If you are struggling to build muscle despite consistent resistance training, your baseline cellular machinery (ribosomes) might be a limiting factor, but this is largely genetic or determined by prior activity levels. The key takeaway is that 'more' isn't always 'better' for muscle growth; your body may adapt by becoming more efficient with what it has rather than expanding its capacity. Focus on progressive overload and consistency, as the body's response is individual and not strictly dictated by having the highest possible baseline ribosome levels.