Research
Hormonal
A two-meals-a-day ketogenic diet may cause an increase in serum uric acid levels in patients with type 2 diabetes.
Monitor uric acid levels when starting this diet, as it may rise. This is a known trade-off of ketosis.
ModerateQualifiesMEDIUM confidence
In addition, the 2-meals-a-day KD group showed a slight increase in uric acid levels compared to the conventional diabetic diet control group (P < .05).
Why this rating
Retrospective observational study, small sample.
Source
Effects of a two meals-a-day ketogenic diet on newly diagnosed obese patients with type 2 diabetes mellitus: A retrospective observational study
Sumei Li et al. · Medicine · 2023
DOI 10.1097/md.0000000000035753
cohort · n=60Cited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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