Hormonal
Semaglutide 2.4 mg combined with the WeGoTogether digital support program yields substantial long-term weight loss, with mean percent weight loss reaching -20.4% at 24 months in a real-world setting.
If you have a BMI of 25 or higher, starting semaglutide 2.4 mg and using a digital support app like WeGoTogether can help you lose a significant amount of weight over two years. The app provides reminders, coaching, and tools to help you stay on track. Expect to lose around 20% of your body weight by the end of two years, based on this study's findings.
Among all patients (BMI ≥ 25.0 kg/m2), the mean (SD) percent weight loss from the index date was − 13.4% (6.4%) at 6 months (n = 6964), − 17.6% (10.2%) at 12 months (n = 2050), − 20.3% (11.4%) at 18 months (n = 491), and − 20.4% (11.3%) at 24 months (n = 325).
Why this rating
Large sample size (n=8177) and long duration (24 months), but retrospective, non-interventional, and relies on self-reported data.
Source
Real-World Weight Loss Among Patients Initiating Semaglutide 2.4 mg and Enrolled in WeGoTogether, a Digital Self-Support Application
Joshua C. Toliver et al. · Advances in Therapy · 2025
DOI 10.1007/s12325-025-03325-1
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