Research
Macro partitioning
Orlistat, taken at 120 mg three times daily, reduces body weight by 8% over 12 months compared to 5% with placebo, and significantly reduces cardiovascular risk factors like hypertension and LDL cholesterol.
Orlistat (120 mg, 3 times daily) helps you lose about 8% of your body weight over a year by blocking fat absorption. It also lowers blood pressure and LDL cholesterol. You must follow a low-fat diet and take vitamin supplements to avoid side effects like oily stools.
GoodSupportsHIGH confidence
Em doses de 120 mg 3x ao dia, durante 12 meses, teve resultados de redução de peso de 8%, comparado aos 5% do placebo. Tais resultados foram ainda mais significativos quando em associação a dietas de baixa ingesta de gordura... O uso do orlistat mostrou ser capaz de reduzir de forma significante os fatores de risco cardiovasculares gerados pela obesidade, como a hipertensão arterial e os níveis de colesterol LDL.
Why this rating
Based on clinical studies and umbrella reviews of systematic reviews.
Source
TERAPIAS FARMACOLÓGICAS PARA TRATAR OBESIDADE: ANÁLISE DE EFEITO E EFICÁCIA
Túlio Martins Freitas et al. · Revista Foco · 2024
DOI 10.54751/revistafoco.v17n10-082
narrative_reviewCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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