Hormonal
GLP-1 receptor agonists (e.g., Semaglutide) are effective for weight loss and metabolic stabilization but cause significant weight regain (rebound) upon discontinuation, necessitating long-term management or transition to surgery.
GLP-1 medications like Semaglutide are powerful tools for weight loss and fixing metabolic issues, but they are not a one-time cure. If you stop taking them, you will likely regain most of the weight. Use them to stabilize your health and weight before considering skin removal surgery, or commit to long-term use if surgery is not an option.
Дані багатоцентрового дослідження STEP 4 свідчать, що після припинення введення семаглутіду пацієнти... протягом року відновили до двох третин втраченої маси тіла. Це вказує на те, що ефект препарату є значною мірою оборотним...
Why this rating
Cites specific multi-center trial data (STEP 4).
Source
Comprehensive approach to the treatment of patients with aesthetic deformity of the anterior abdominal wall with concomitant metabolic disorders
Todurov et al. · Diabetes Obesity Metabolic Syndrome · 2025
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