Research
Hormonal
Smoking cessation leads to significant weight gain and metabolic deterioration, but the cardiovascular benefits of quitting smoking outweigh these risks.
If you smoke, quit. You will likely gain some weight, but this does not cancel out the massive heart health benefits of quitting. Focus on healthy habits to manage weight, but do not let the fear of weight gain stop you from quitting.
StrongQualifiesVERY_HIGH confidence
Smoking cessation causes significant weight gain and consequent deterioration of the metabolic profile despite not impairing the cardiovascular benefits.
Why this rating
Supported by strong evidence from multiple studies and meta-analyses.
Source
Body Weight Change and Cardiovascular Disease: Effect of Weight Gain, Weight Loss, and Weight Cycling
Jung Hwan Cho et al. · Cardiovascular Prevention and Pharmacotherapy · 2021
DOI 10.36011/cpp.2021.3.e12
narrative_reviewCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Intentional weight loss through lifestyle modifications or pharmacotherapy provides consistent cardiovascular protective effects by improving metabolic profiles and cardiac structure.Good
- Weight cycling (losing and regaining weight) is associated with unfavorable cardiometabolic profiles and increased cardiovascular disease risk.Good
- Unintentional weight loss is independently associated with increased cardiovascular disease incidence and mortality.Good
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