Research

Macro partitioning

High adherence to the Mediterranean diet is characterized by a macronutrient profile with lower carbohydrate (46-49%) and higher protein (19-22%) and fat (31-33%) intake compared to standard recommendations, which is significantly associated with lower adiposity and inflammation.

If you follow a Mediterranean-style diet, focus on keeping carbohydrates on the lower end of the recommended range (around 46-49% of calories) while ensuring adequate protein (19-22%) and healthy fats (31-33%). This specific balance is linked to lower body fat and reduced inflammation compared to standard high-carb interpretations of the diet.

GoodQualifiesHIGH confidence
H-MD is characterised by lower carbohydrate, higher protein and fat intakes than those usually reported in nutritional recommendations. This profile was significantly associated with lower adiposity and inflammation.
Claudia Vetrani et al. · Journal of Translational Medicine · 2025

Why this rating

Large cross-sectional sample (n=1342) with rigorous dietary assessment (7-day food records) and clinical biomarkers, though causality cannot be established.

Source

Actual macronutrient composition of the Mediterranean diet and its association with adiposity and inflammation: a cross-sectional real-life study

Claudia Vetrani et al. · Journal of Translational Medicine · 2025

cross_sectional · n=1342Cited 1×
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