Research

Macro partitioning

Dietary fat intake, particularly unsaturated fatty acids (UFA), is associated with reduced mortality and cardiovascular disease incidence, challenging standard guidelines that recommend limiting saturated fat (SFA).

Focus on the quality of fats rather than just minimizing total fat. Prioritize unsaturated fats (like olive oil) over saturated fats, but do not fear dietary fat as a primary cause of heart disease. Ensure your carbohydrate intake is not excessively high, especially if you are from a population with high carb consumption.

ModerateSupportsMEDIUM confidence
Their results are consistent with evidence suggesting that a diet high in fat might reduce mortality and incidence of cardiovascular disease.
Salvatore Carbone et al. · The Lancet · 2018

Why this rating

Based on a large prospective cohort (PURE) but acknowledged to have methodological limitations regarding food frequency questionnaires.

Source

Associations of fats and carbohydrates with cardiovascular disease and mortality—PURE and simple?

Salvatore Carbone et al. · The Lancet · 2018

DOI 10.1016/s0140-6736(18)30799-2

narrative_reviewCited 1×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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