Research
Hormonal
Neurotensin (Nts) neurons in the LHA are implicated in coordinating anorectic stimuli and behavior to regulate hydration and energy balance.
Neurotensin neurons in the LHA are emerging as important regulators of hydration and energy balance. Further research is needed to fully understand their role and potential therapeutic applications.
ModerateSupportsMEDIUM confidence
Recently, another population of LHA neurons containing the neuropeptide Neurotensin (Nts) has been implicated in coordinating anorectic stimuli and behavior to regulate hydration and energy balance.
Why this rating
Based on emerging research, less extensive than MCH and OX studies.
Source
To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance
Juliette A. Brown et al. · Frontiers in Systems Neuroscience · 2015
DOI 10.3389/fnsys.2015.00009
narrative_reviewCited 99×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Lateral hypothalamic area (LHA) neurons coordinate energy balance by integrating peripheral nutrient cues with ingestive, locomotor, and arousal behaviors.Good
- Melanin-concentrating hormone (MCH) neurons in the LHA promote feeding and general intake behavior, while their blockade can increase energy expenditure and promote weight loss.Good
- Orexin (OX) neurons in the LHA promote feeding, arousal, and physical activity, and their disruption is linked to sleep disorders like narcolepsy.Good
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