Hormonal
GLP-1 receptor agonists (Liraglutide, Semaglutide) and dual GIP/GLP-1 agonists (Tirzepatide) produce significant, sustained weight loss in adults with obesity or overweight with comorbidities, outperforming placebo.
If lifestyle changes haven't led to sufficient weight loss, consult a doctor about GLP-1 medications like Liraglutide or Semaglutide. These are prescribed for BMI ≥ 30 (or ≥ 27 with health issues) and work by mimicking gut hormones to reduce appetite and slow digestion. Treatment is most effective when combined with diet and exercise, and must be stopped if less than 5% weight loss occurs after 12 weeks.
Liraglutid und Semaglutid sowie der neue GIP/GLP-1-Rezeptoragonist Tirzepatid haben in jüngster Zeit ihre gewichtsreduzierenden Eigenschaften unter Beweis gestellt.
Why this rating
Based on multiple Phase III randomized controlled trials (SCALE, STEP 1, SURMOUNT-1) cited in the review.
Source
Neue Behandlungsmöglichkeiten der Adipositas
Ellen Heitlinger et al. · 2024
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