Research

Adherence

A personalized lifestyle coaching program combining multi-omic data with behavioral support produces clinically meaningful improvements in HbA1c comparable to landmark randomized controlled trials.

Making sustainable lifestyle changes through coaching can lower your blood sugar levels (HbA1c) just as effectively as intensive lifestyle programs used in major medical trials. This means that consistent, coached changes to diet and activity can have a powerful impact on your diabetes risk, potentially avoiding or delaying the need for medication.

ModerateSupportsMEDIUM confidence
we found an adjusted average decrease in HbA1c of about 0.20% at 12 months in the entire study population... The Diabetes Prevention Program, a RCT comparing intensive lifestyle intervention vs. metformin/standard care, saw slightly less than a 0.1% decrease in HbA1c at 12 months for those in the lifestyle intervention arm.
Niha Zubair et al. · Scientific Reports · 2019

Why this rating

Observational study without a control group; results are compared to an external RCT, but internal validity is limited by lack of randomization.

Source

Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program

Niha Zubair et al. · Scientific Reports · 2019

DOI 10.1038/s41598-019-43058-0

cohort · n=2531Cited 96×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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