Hormonal
Phenotype-guided pharmacotherapy (matching drug mechanism to obesity phenotype) yields significantly greater weight loss than non-phenotype-guided approaches.
If you are struggling with obesity, ask your doctor about 'phenotyping.' Instead of just taking the most common weight loss drug, see if your specific type of hunger (e.g., emotional, hormonal, or slow metabolism) matches a specific medication. This personalized matching has been shown to result in significantly more weight loss than standard approaches.
This important study found that phenotype-guided treatment resulted in 1.75 times greater weight loss (15.9% total) over 12 months compared to non-phenotype-guided approaches [12].
Why this rating
Based on a cited pragmatic trial (Acosta et al., 2021) referenced in the review.
Source
Challenges and Novelties in the Treatment of Obesity in Adults. A review
Karolina Kuczapska et al. · Journal of Education Health and Sport · 2025
DOI 10.12775/jehs.2025.77.57095
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Related findings · Hormonal
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This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →