Research

Macro partitioning

In individuals with type 2 diabetes, a carbohydrate-reduced high-protein (CRHP) diet (30E% carbs, 30E% protein, 40E% fat) induces greater improvements in glycaemic control (HbA1c, diurnal glucose) and reduces liver fat compared to a conventional diabetes diet (50E% carbs, 17E% protein, 33E% fat), even when both diets produce matched weight loss.

For a person with Type 2 Diabetes, switching to a diet with 30% of calories from carbs, 30% from protein, and 40% from fat (while maintaining a calorie deficit to lose weight) can improve blood sugar control and reduce liver fat more effectively than a standard high-carb diabetes diet, even if both diets result in the same amount of weight loss. However, be aware that this diet may not reduce fat stored in the pancreas as much as a standard diet.

WeakSupportsHIGH confidence
Compared with the CD diet, the CRHP diet further reduced HbA1c... and diurnal mean glucose... and augmented the reductions in... liver fat content... However, pancreatic fat content was decreased to a lesser extent by the CRHP than the CD diet.
Mads N. Thomsen et al. · Diabetologia · 2022

Why this rating

Randomized Controlled Trial (RCT) with matched weight loss, objective measures (CGM, MR spectroscopy), and clear statistical significance.

Source

Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: a randomised controlled trial

Mads N. Thomsen et al. · Diabetologia · 2022

DOI 10.1007/s00125-021-05628-8

rct · n=72Cited 86×
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DOI resolved against Crossref · corpus check 2026-06-10

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