Research
Hormonal
Tirzepatide significantly reduced body weight compared to placebo, with a total pooled mean difference of -11.62 kg (95% confidence interval: -14.24 to -9.01, p < 0.001).
Tirzepatide can be considered an effective treatment option for weight loss in adults with obesity.
StrongSupportsmedium confidence
Tirzepatide significantly reduced body weight compared to placebo, with a total pooled mean difference of -11.62 kg (95% confidence interval: -14.24 to -9.01, p < 0.001).
Why this rating
Based on a systematic review and meta-analysis of randomized controlled trials.
Source
Exploring the Efficacy and Safety of Tirzepatide in Obesity Management and Cardiometabolic Risk Factors: A Comprehensive Systematic Review and Meta‐Analysis
Jian‐Ying Wang et al. · Clinical Obesity · 2025
Meta-analysisCited 1×
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