Research
Hormonal
Tirzepatide and weekly semaglutide demonstrated comparable results but with significantly higher odds of achieving ≥5%–20% weight loss compared with liraglutide.
Both tirzepatide and semaglutide are viable options for achieving significant weight loss, with tirzepatide having an edge.
StrongSupportsmedium confidence
Tirzepatide and weekly semaglutide demonstrated comparable results but with significantly higher odds of achieving ≥5%–20% weight loss compared with liraglutide.
Why this rating
Based on a network meta-analysis of seven RCTs with over 12,300 patients.
Source
Comparative effectiveness of glucagon‐like peptide‐1 receptor agonists for the management of obesity in adults without diabetes: A network meta‐analysis of randomized clinical trials
Omar S. Alkhezi et al. · Obesity Reviews · 2022
Meta-analysisCited 132×
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