Hormonal
Carbohydrate restriction, particularly very-low-carbohydrate (VLC) or ketogenic diets, significantly improves glycemic control (lower HbA1c), reduces insulin requirements, and stabilizes blood glucose profiles in patients with Type 1 Diabetes (T1D) compared to standard high-carbohydrate diets.
For T1D patients, adopting a very-low-carbohydrate diet (under 50g carbs/day) can significantly stabilize blood sugar and reduce the amount of insulin needed. This approach lowers the risk of both high and low blood sugar spikes. However, it requires careful medical supervision to safely reduce insulin doses and avoid hypoglycemia during the transition.
all LC and VLC studies reported mean HbA1c of less than 7.5%... CGM showed remarkably stable glycemic profiles... short-term RCTs comparing LC or VLC with HC diets showed reductions in HbA1c, insulin doses, glycemic variability, and time spent in hypoglycemia.
Why this rating
The paper cites multiple RCTs and observational studies showing benefit, but notes limitations such as small sample sizes, short duration, and lack of long-term hard outcome data.
Source
Carbohydrate restriction for diabetes: rediscovering centuries-old wisdom
Belinda Lennerz et al. · Journal of Clinical Investigation · 2021
DOI 10.1172/jci142246
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