Hormonal
Following 16 weeks of resistance training, the acute activation of muscle satellite cells (SC) in response to a single bout of exercise is augmented (increased Pax7+/MyoD+ cells and MyoD mRNA expression at 24h), which is accompanied by increased muscle fiber capillarization.
If you have been resistance training consistently for a few months, your muscles become more efficient at repairing themselves after a workout. Specifically, your muscle stem cells activate faster (within 24 hours) and express more growth-related genes (MyoD) after a single intense session compared to when you were a beginner. This suggests that long-term training enhances the muscle's ability to adapt to acute stress, likely supported by improved blood flow (capillarization) in the muscle.
Following RT, there was a greater activation of SC after 24h in response to a single bout of resistance exercise... Following 16wk of RT, MyoD mRNA expression increased from basal to 24h after the single bout of exercise... Following 16wk of RT, enhanced activation of SC in response to resistance exercise is accompanied by increases in muscle fiber capillarization.
Why this rating
Randomized controlled trial design with pre/post measurements, clear statistical significance (p<0.05), and objective histological/molecular markers.
Source
Altered muscle satellite cell activation following 16 wk of resistance training in young men
Joshua P. Nederveen et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2016
DOI 10.1152/ajpregu.00221.2016
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