Research
Hormonal
Insulin regulates free fatty acid appearance into plasma (FFA R(a)) by inhibition of lipolysis while maintaining a constant rate of primary FFA reesterification.
Practitioners should consider that insulin plays a crucial role in regulating fat metabolism by inhibiting fat breakdown.
StrongSupportsmedium confidence
In conclusion, insulin regulates FFA R(a) by inhibition of lipolysis while maintaining a constant rate of primary FFA reesterification.
Why this rating
Based on the study design involving human subjects and multiple insulin infusion rates.
Source
Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification
Peter J. Campbell et al. · American Journal of Physiology-Endocrinology and Metabolism · 1992
DOI 10.1152/ajpendo.1992.263.6.e1063
other · n=7Cited 120×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- The proportion of free fatty acid molecules undergoing primary reesterification doubled over the physiological portion of the insulin dose-response curve.Strong
- Lipolysis, free fatty acid appearance into plasma (FFA R(a)), and secondary free fatty acid reesterification are exquisitely insulin sensitive.Strong
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