Research

Hormonal

Tirzepatide treatment was associated with lower hazards of all-cause mortality compared to GLP-1 RA (adjusted hazard ratio [AHR], 0.58; 95% CI, 0.45-0.75).

Practitioners may consider tirzepatide as a safer option for reducing mortality risk in patients with type 2 diabetes.

StrongSupportsmedium confidence
Tirzepatide treatment was associated with lower hazards of all-cause mortality (adjusted hazard ratio [AHR], 0.58; 95% CI, 0.45-0.75).
Min‐Hsiang Chuang et al. · JAMA Network Open · 2024

Why this rating

Based on a large retrospective cohort study design.

Source

Clinical Outcomes of Tirzepatide or GLP-1 Receptor Agonists in Individuals With Type 2 Diabetes

Min‐Hsiang Chuang et al. · JAMA Network Open · 2024

cohort · n=140308Cited 106×
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