Research
Hormonal
Fasting ghrelin levels significantly increased from baseline in all three intervention groups.
Dietary interventions may increase ghrelin levels, which could influence hunger and metabolism.
StrongSupportsmedium confidence
Fasting ghrelin was significantly increased from baseline in all three intervention groups.
Why this rating
Based on study design from abstract.
Source
The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women
Leanne M. Redman et al. · Aging Cell · 2009
DOI 10.1111/j.1474-9726.2009.00530.x
rct · n=43Cited 61×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →