Research
Hormonal
GLP1-RA treatment is associated with improvements in mental health-related quality of life compared with placebo (g = 0.15; P < .001).
GLP1-RAs may enhance mental health quality of life in this population.
StrongSupportsmedium confidence
GLP1-RA treatment was associated with improvements in mental health-related QOL (g = 0.15; 95% CI, 0.07 to 0.22; P < .001).
Why this rating
Based on a meta-analysis of randomized clinical trials.
Source
Glucagon-Like Peptide 1 Receptor Agonists and Mental Health
Aureliane C. S. Pierret et al. · JAMA Psychiatry · 2025
Meta-analysisCited 61×
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