Hormonal
Acute endurance exercise increases skeletal muscle Perilipin 3 (PLIN3) and coatomer GTPase proteins, and this increase is positively associated with fat oxidation.
Engaging in long-duration endurance exercise (e.g., cycling at 50% VO2max until 650 kcal is expended) triggers an increase in specific proteins (PLIN3 and coatomers) in your skeletal muscle. This molecular change is directly linked to your body's ability to oxidize fat during and after the workout. To leverage this, prioritize steady-state cardio sessions that are long enough to stimulate these adaptations.
a long duration endurance exercise bout (20 males; age 24.064.5 y; BMI 23.661.8 kg/m2) increased PLIN3 protein in human skeletal muscle (p = 0.03) in proportion to ex vivo palmitate oxidation (r = 0.45, p = 0.04) and whole body in vivo fat oxidation (r = 0.52, p = 0.03).
Why this rating
Observational study with a small sample size (n=20, with molecular data from 14-19 participants) and acute intervention only.
Source
Skeletal Muscle Perilipin 3 and Coatomer Proteins Are Increased following Exercise and Are Associated with Fat Oxidation
Jeffrey D. Covington et al. · PLoS ONE · 2014
DOI 10.1371/journal.pone.0091675
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