Research
Hormonal
Insulin and homeostasis model assessment decreased significantly with diet type II in both genotypes.
Diet type II may improve insulin sensitivity in this population.
StrongSupportsmedium confidence
With the diet type II and in both genotypes (wild and mutant type), insulin (-5.2 ± 6.1 vs. -3.8 ± 6.1 IU/L; p < 0.05) and homeostasis model assessment (-2.4 ± 4.8 vs. -1.1 ± 3.8 kg; p < 0.05) decreased.
Why this rating
Based on the prospective design with statistical significance.
Source
Evaluation of weight loss and adipocytokines levels after two hypocaloric diets with different macronutrient distribution in obese subjects with rs9939609 gene variant
Daniel Antonio de Luis et al. · Diabetes/Metabolism Research and Reviews · 2012
DOI 10.1002/dmrr.2323
cohort · n=305Cited 47×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Weight, fat mass, waist circumference, and systolic blood pressure decreased after treatment with both diets in obese subjects with the rs9939609 gene variant.Strong
- Total cholesterol, low-density lipoprotein cholesterol, and C-reactive protein levels significantly decreased in the A allele group after treatment with diet II.Strong
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