Research
Hormonal
GLP-1 RA treatment was associated with a significantly lower risk of all-cause mortality (hazard ratio 0.23; 95% confidence interval 0.15-0.34).
GLP-1 RAs may significantly reduce the risk of death in obese individuals without T2D.
StrongSupportsmedium confidence
GLP-1 RA treatment was associated with a significantly lower risk of all-cause mortality (hazard ratio 0.23; 95% confidence interval 0.15-0.34).
Why this rating
Based on a large observational cohort study design.
Source
Long‐term safety and efficacy of glucagon‐like peptide‐1 receptor agonists in individuals with obesity and without type 2 diabetes: A global retrospective cohort study
Yu‐Nan Huang et al. · Diabetes Obesity and Metabolism · 2024
cohort · n=3729925Cited 34×
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