Research
Hormonal
Reductions in visceral adiposity and estimated liver fat are associated with improvements in the ISI-Matsuda index over 3 years.
Targeting visceral fat reduction may enhance insulin sensitivity in interventions.
StrongSupportsmedium confidence
Multivariate analysis revealed that both visceral adiposity and estimated liver fat reductions contributed to the improved ISI-Matsuda index observed over 3 yr.
Why this rating
The study's multivariate analysis supports the claim.
Source
Cardiometabolic risk improvement in response to a 3-yr lifestyle modification program in men: contribution of improved cardiorespiratory fitness vs. weight loss
Anne‐Laure Borel et al. · American Journal of Physiology-Endocrinology and Metabolism · 2016
DOI 10.1152/ajpendo.00278.2016
cohort · n=94Cited 30×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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