Research
Hormonal
Preoperative semaglutide use in patients with type II diabetes mellitus undergoing arthroscopic rotator cuff repair was associated with a lower incidence of any adverse events (11.0% vs 27.4%), severe adverse events (3.5% vs 10.5%), and minor adverse events (8.5% vs 22.0%) within 90 days post-surgery.
Practitioners may consider semaglutide as a beneficial preoperative intervention to reduce postoperative complications in diabetic patients.
StrongSupportsmedium confidence
The incidence of AAE for the ARCR (-)semaglutide versus ARCR (+)semaglutide patients was 27.4% versus 11.0%, SAE was 10.5% versus 3.5%, and MAE was 22.0% versus 8.5%, respectively (P < .001 for all).
Why this rating
Based on the comparative study design with a large sample size.
Source
Lower Risk of Postoperative Complications and Rotator Cuff Retear Associated With Semaglutide Use in Patients with Type II Diabetes Mellitus Undergoing Arthroscopic Rotator Cuff Repair
Anthony E Seddio et al. · Arthroscopy The Journal of Arthroscopic and Related Surgery · 2024
cohort · n=5204Cited 15×
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