Research
Hormonal
Incretin-based therapies showed a greater effect on AHI compared to usual care, with a mean difference of -11.61 events/h.
Incretin-based therapies may be more effective than usual care for improving AHI in OSA patients.
StrongSupportsmedium confidence
By pooling data of 5 RCTs in a pairwise meta-analysis, incretin-based therapies showed a greater effect on AHI than usual care, with a mean difference of -11.61 events/h (95 % CI: 22.91 to -0.31, p = 0.046).
Why this rating
Based on a meta-analysis of randomized controlled trials.
Source
Efficacy of incretin-based therapies in obesity-related obstructive sleep apnea: a systematic review and meta-analysis of randomized controlled trials
Anna Bardóczi et al. · Sleep Medicine Reviews · 2025
DOI 10.1016/j.smrv.2025.102119
Meta-analysisCited 12×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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