Research

Hormonal

Acute L-arginine supplementation (6-8g) provides no ergogenic effect on strength training performance metrics such as muscular endurance, peak torque, or resistance rate.

If you are looking to improve your strength training performance (max reps, peak torque, or endurance), taking 6-8 grams of L-arginine shortly before your workout will not provide a performance benefit compared to a placebo. The current evidence does not support its use as an ergogenic aid for strength athletes.

ModerateRefutesMEDIUM confidence
Acute L-arginine supplementation provides no ergogenic effect on strength training performance.
Camila Pasa et al. · F1000Research · 2021

Why this rating

Moderate quality evidence based on GRADE score, though limited by small sample size (n=30) and only 3 studies.

Source

Effectiveness of acute L-arginine supplementation on physical performance in strength training: a systematic review and meta-analysis

Camila Pasa et al. · F1000Research · 2021

DOI 10.12688/f1000research.73905.1

Meta-analysis · 3 studies
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →