Energy balance
Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.
If you have recently been diagnosed with Type 2 Diabetes, focus on losing 10-15% of your body weight. The most effective way to do this, according to current evidence, is using a Total Diet Replacement program (like liquid formula meals) for 12 weeks, followed by a structured transition to healthy food. This approach is more likely to put your diabetes into remission than low-carb diets or medication alone. Be prepared to work with your doctor to safely stop diabetes medications during the weight loss phase, and have a plan for maintenance support to keep the weight off.
Surgical and non-surgical weight loss studies (2–5) have conclusively demonstrated that 10-15% body weight loss will lead to remission of type 2 diabetes (HbA1c<48 mmol/mol, without glucose-lowering medication for at least 3 months) in the majority of individuals with short duration disease.
Why this rating
Based on high-quality Randomized Controlled Trials (DiRECT, DIADEM-I) and systematic reviews.
Source
Total Diet Replacement Within an Integrated Intensive Lifestyle Intervention for Remission of Type 2 Diabetes: Lessons From DiRECT
Jarvis C. Noronha et al. · Frontiers in Endocrinology · 2022
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