Research
Hormonal
Retatrutide raises cardiovascular safety concerns due to dose-dependent increases in heart rate and incidents of mild to moderate cardiac arrhythmias.
Clinicians should monitor cardiovascular health in patients using retatrutide.
StrongQualifiesmedium confidence
Dose-dependent increase in heart rate and incidents of mild to moderate cardiac arrythmias raise cardiovascular safety concerns.
Why this rating
Based on phase-2 trial data mentioned in the abstract.
Source
Retatrutide: a triple incretin receptor agonist for obesity management
Avik Ray · Expert Opinion on Investigational Drugs · 2023
DOI 10.1080/13543784.2023.2276754
reviewCited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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