Macro partitioning
Higher dietary intake of polyunsaturated fatty acids (PUFAs) is associated with a lower risk of heart disease mortality in adults without prior myocardial infarction, whereas saturated (SFAs) and monounsaturated fatty acids (MUFAs) show no such association.
For heart health prevention, focus on increasing polyunsaturated fats (found in fish, nuts, seeds, and vegetable oils) rather than just cutting saturated fats. This benefit appears strongest for people who have not yet had a heart attack. If you have existing heart disease, dietary changes alone may not be sufficient to reduce mortality risk, and medical management is critical.
Higher intake of PUFAs, but not SFAs and MUFAs, was associated with a lower adjusted risk of heart disease mortality in a large population of US adults supporting the need to increase dietary PUFA intake in the general public.
Why this rating
Large observational cohort (N=45,820) with long follow-up, but subject to residual confounding despite adjustments.
Source
Dietary fatty acids and mortality risk from heart disease in US adults: an analysis based on NHANES
Yutang Wang et al. · Scientific Reports · 2023
DOI 10.1038/s41598-023-28738-2
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →