Research
Metabolic adaptation
Substituting carbohydrates with total fat, but not SFA, was associated with significantly lower risk of CHD (HR 0·75, 95 % CI 0·62, 0·90).
Practitioners may consider recommending fat sources over carbohydrates to lower CHD risk.
GoodSupportsmedium confidence
A 5 E% substitution of carbohydrates with total fat, but not SFA, was associated with lower CHD risk (HR 0·75, 95 % CI 0·62, 0·90).
Why this rating
Based on the prospective cohort study design.
Source
Intake of carbohydrates and SFA and risk of CHD in middle-age adults: The Hordaland Health Study (HUSK)
Haugsgjerd et al. · Duo Research Archive (University of Oslo) · 2020
cohort · n=2995Cited 8×
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