Research
Hormonal
Liraglutide (3.0 mg daily) and semaglutide (2.4 mg weekly) are FDA-approved GLP-1 receptor agonists for weight management.
Practitioners can consider liraglutide and semaglutide as viable options for patients needing weight management.
StrongSupportsmedium confidence
Two injectable incretin-based glucagon-like peptide-1 (GLP-1) receptor agonists — liraglutide (3.0 mg daily) and semaglutide (2.4 mg weekly) — have been approved by the Food and Drug Administration (FDA) for weight management.
Why this rating
The claim is based on FDA approval, indicating a high level of evidence.
Source
Next Chapter for Weight Control — Small-Molecule GLP-1 Receptor Agonists?
E. Dale Abel · New England Journal of Medicine · 2023
DOI 10.1056/nejme2307285
reviewCited 7×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
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- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
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