Research
Hormonal
Glycerol concentration increased by GIP (+13%) and GLP-1/GIP/glucagon receptor triagonist (+28%) in human adipose tissue.
GIP may be a potential target for enhancing fat loss in overweight individuals.
StrongSupportsmedium confidence
Glycerol concentration only increased by isoprenaline, GIP (+13%), and GLP-1/GIP/glucagon receptor triagonist (+28%) but not by GLP-1 or glucagon.
Why this rating
Based on the study design involving isolated primary adipocytes from human subjects.
Source
Hormonal regulation of human adipose tissue lipolysis: impact of adipose GIP system in overweight and obesity
Sebastian Brachs et al. · European Journal of Endocrinology · 2025
DOI 10.1093/ejendo/lvae151
other · n=22Cited 6×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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