Research
Hormonal
The study revealed sex-specific mediating effects of sex hormones due to weight loss from intensive lifestyle intervention on body composition changes in people with type 2 diabetes.
Practitioners should tailor weight loss recommendations based on sex differences in hormone responses.
StrongSupportsmedium confidence
This study revealed sex-specific mediating effects of sex hormones due to weight loss from ILI on body composition changes in people with T2D.
Why this rating
Based on the analysis of a large participant group in a structured study.
Source
Role of Sex Hormones in Mediating Adiposity Changes From Weight Loss in People With Type 2 Diabetes: Look AHEAD Sex Hormone Study
Chigolum P. Oyeka et al. · The Journal of Clinical Endocrinology & Metabolism · 2025
cohort · n=2334Cited 7×
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