Macro partitioning
Post-exercise high-fat feeding suppresses p70S6K1 activity in human skeletal muscle, potentially impairing muscle protein synthesis and remodeling despite adequate protein intake.
If your goal is maximizing muscle growth or remodeling after training, consuming a high-fat meal immediately post-exercise may blunt the signaling pathways (p70S6K1) responsible for building muscle, even if you eat enough protein. Consider prioritizing carbohydrates or lower-fat protein sources in the immediate recovery window to optimize anabolic signaling.
p70S6K activity was higher (P=0.08) at 3 h post-SS exercise in HCHO versus HFAT (72.7 ± 51.9 vs 44.7 ± 27 fmol.min-1 mg-1)... Conclusion: ...post-exercise p70S6K1 activity is reduced under conditions of high fat feeding thus potentially impairing skeletal muscle remodelling processes.
Why this rating
Small sample size (n=10), acute design, and p=0.08 (trend) for the primary outcome, though statistically significant for secondary lipid markers.
Source
Postexercise High-Fat Feeding Suppresses p70S6K1 Activity in Human Skeletal Muscle
Kelly M. Hammond et al. · Medicine & Science in Sports & Exercise · 2016
DOI 10.1249/mss.0000000000001009
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →