Research
Hormonal
GLP-1 receptor agonists reduced systolic blood pressure (SBP) by 3.4 mmHg and diastolic blood pressure (DBP) by 0.9 mmHg.
GLP-1 receptor agonists can be considered for managing blood pressure in overweight or obese patients.
StrongSupportsmedium confidence
GLP1-RAs reduced SBP by 3.4 mmHg (95% CI 2.8-4.0) and DBP by 0.9 mmHg (95% CI 0.5-1.2).
Why this rating
Based on a systematic review and meta-analysis of 85 RCTs.
Source
Effect of incretin-based therapies on blood pressure: a systematic review and meta-analysis
Christian Basile et al. · European Journal of Preventive Cardiology · 2025
DOI 10.1093/eurjpc/zwaf560
Meta-analysisCited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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