Research

Hormonal

Semaglutide had substantial effects on multiple secondary alcohol-related and somatic outcomes.

Semaglutide may improve various aspects of health related to alcohol use disorder in addition to reducing drinking.

StrongSupportsmedium confidence
Semaglutide...had substantial effects on multiple secondary alcohol-related and somatic outcomes.
Mette Kruse Klausen et al. · The Lancet · 2026

Why this rating

Based on the randomized, double-blind, placebo-controlled trial design.

Source

Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial

Mette Kruse Klausen et al. · The Lancet · 2026

rct · n=108Cited 4×
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