Research
Hormonal
Semaglutide improved heart failure symptoms and physical limitations in participants with obesity-related HFpEF.
Practitioners can consider semaglutide as an effective treatment for improving symptoms in patients with obesity-related HFpEF.
StrongSupportsmedium confidence
In the STEP-HFpEF program, semaglutide improved heart failure (HF) symptoms and physical limitations and reduced body weight (BW) in participants with obesity-related HFpEF.
Why this rating
Based on the large RCT design of the STEP-HFpEF program.
Source
Frailty and Effects of Semaglutide in Obesity-Related HFpEF
Ambarish Pandey et al. · JACC Heart Failure · 2025
rctCited 4×
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