Research
Hormonal
Semaglutide treatment shows significant interactions based on sex at both 1.7 mg and 2.4 mg doses compared to placebo.
Clinicians should consider sex as a factor when prescribing semaglutide for weight loss.
StrongSupportsmedium confidence
Significant treatment-by-subgroup interactions were observed for sex with semaglutide 1.7 mg and 2.4 mg versus placebo at week 68 (p = 0.0008 and p = 0.0005, respectively).
Why this rating
Based on the randomized controlled trial design of STEP 6.
Source
Clinical characteristics affecting weight loss in an East Asian population receiving semaglutide: A STEP 6 subgroup analysis
Takashi Kadowaki et al. · Obesity Research & Clinical Practice · 2024
rct · n=401Cited 4×
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