Browse the evidence

The intestinal microbiota may play a central role in the relationship between obesity and asthma.

Understanding microbiota's role may inform treatment strategies for asthma in obese patients.

The addition of 5% watermelon seed flour (WSF) to low-carbohydrate, high-protein bread enhances its volume compared to the control sample.

Incorporating 5% WSF can improve the volume of low-carb, high-protein bread.

Most upper airway anatomy was significantly associated with BMI among patients with OSA.

Practitioners should consider the impact of BMI on upper airway anatomy when assessing OSA.

All pharyngeal soft tissues were larger with greater BMI, including the volumes of the tongue, soft palate, and lateral walls.

Increased soft tissue volume with higher BMI should be considered in OSA management.

Female sex, older age, and lower BMI were associated with subsequent lower muscle density in older community-dwelling adults.

Practitioners should consider sex, age, and BMI when assessing muscle density in older adults.

Lower FMD was related to increased risk of previous fracture.

Monitoring FMD may help identify individuals at higher risk for fractures.

Changes in muscle density over time might precede adverse outcomes such as falls and fractures.

Practitioners should monitor muscle density as a potential indicator of future health risks.

The degree of velum and tongue base obstruction was significantly associated with sleep apnea severity in positions 2, 3, and 4 after adjusting for age, BMI, tonsil size, and tongue position.

Understanding the specific obstructions can guide targeted treatments for sleep apnea.

Sodium-glucose cotransporter 2 (SGLT2) inhibitors provide cardiovascular and renal protection in patients with type 2 diabetes mellitus (T2DM).

Practitioners should consider SGLT2 inhibitors as a treatment option for cardiovascular and renal protection in T2DM patients.

Polymeric biomaterials can mimic gastric bypass by blocking excessive absorption.

Practitioners may explore less invasive methods for obesity treatment using polymeric biomaterials.

Understanding novel mutations in POMC and MC4R/MC3R may help identify strategies for the treatment and diagnosis of obesity, particularly childhood obesity.

This knowledge can guide interventions for childhood obesity.

Antidiabetic medications impact skeletal muscle lipid metabolism.

Practitioners should consider the effects of antidiabetic medications on lipid metabolism when treating patients.

Plasma sodium concentration remained stable throughout exercise.

Maintaining stable plasma sodium levels may be crucial for hydration strategies during exercise.

Delayed onset muscle soreness (DOMS) was lower in the naproxen group, but differences were not statistically significant.

Naproxen may help reduce muscle soreness post-exercise, though not significantly.

Interventions like ASK-1 knockout, nitrate, and melatonin have increased thermogenesis and improved metabolic outcomes.

Consider these interventions to enhance thermogenesis in metabolic health strategies.

Management of cardiovascular risk factors in patients with T2DM is complex and requires consideration of factors other than blood glucose.

Practitioners should adopt a holistic approach to managing CV risk in T2DM patients.

Metabolische unerwünschte Arzneimittelwirkungen (mUAW) von Psychopharmaka umfassen Gewichtszunahme, gestörte Glukosetoleranz, Diabetes mellitus und Dyslipidämie.

Healthcare providers should monitor metabolic parameters in patients on psychotropic medications.

Exercise resulted in a 21 ± 4 fold increase in IL-6 mRNA expression.

Moderately trained individuals experience a significant increase in IL-6 mRNA with exercise.

IL-6 gene expression was unaffected by CHO ingestion.

CHO ingestion does not alter the gene expression of IL-6 during exercise.

Following REX, there were significant elevations in p38 MAPKThr180/Tyr182 phosphorylation compared to rest (~348%) and BFR (~973%) (P<0.05).

Resistance exercise significantly activates specific signaling pathways in inactive individuals.

Endoscopic sleeve gastroplasty (ESG) is associated with fewer complications and faster recovery compared to traditional bariatric surgery.

Clinicians can recommend ESG as a safer alternative for patients who are hesitant about traditional surgery.

Metabolische unerwünschte Arzneimittelwirkungen (mUAW) von Psychopharmaka umfassen Gewichtszunahme, gestörte Glukosetoleranz, Diabetes mellitus und Dyslipidämie.

Healthcare providers should monitor metabolic parameters in patients on psychotropic medications.

Lower body mass index is a significant independent factor for paraspinal muscle atrophy in preoperative lumbar spinal stenosis and lumbar disk herniation patients.

Practitioners should consider body mass index when assessing risk for muscle atrophy in these patients.

Reduced lumbar lordosis angle is a significant independent factor for paraspinal muscle atrophy in preoperative lumbar spinal stenosis and lumbar disk herniation patients.

Practitioners should consider lumbar lordosis angle when assessing risk for muscle atrophy in these patients.