Browse the evidence

Over four years, autoantibody positive participants lost 5.1 kg more weight than autoantibody negative participants.

Autoantibody positivity may influence weight loss outcomes in interventions for type 2 diabetes.

There is high interest in intervening early through nonvolitional exercise strategies such as electrical muscle stimulation (EMS).

Consider using EMS as a nonvolitional exercise strategy to support muscle health in critically ill patients.

In cancer survivors with obesity, metformin treatment resulted in a significant decrease in IGF-1 levels by 7.2 ng/mL at 6 months.

Metformin may be considered as a treatment option for reducing IGF-1 levels in obese cancer survivors.

Obesity is related to a higher incidence of cancer during a lifespan.

Addressing obesity may reduce cancer risk.

Effective treatment of obesity may impact cancer treatment.

Obesity treatment should be considered in cancer care strategies.

The sequential, multiple assignment, randomized trial (SMART) design aids in constructing effective adaptive interventions (AIs).

Practitioners can utilize SMART designs to develop and test AIs effectively.

Personalized diets based on a combination of clinical and microbial features may enable accurate prediction of dietary responses.

Practitioners may consider integrating clinical and microbial data for personalized dietary recommendations.

Defined diets have been tested as preventive and treatment approaches for diseases such as epilepsy, ulcerative colitis, Crohn disease, and type 1 diabetes mellitus.

Defined diets may be considered in clinical settings for managing specific diseases.

Tailored diet regimens have the potential to modulate pharmaceutical treatment efficacy in cancer treatment.

Dietary modifications may enhance the effectiveness of cancer treatments.

Factors associated with remission include shorter duration of diabetes, lower baseline HbA1c, higher baseline BMI, higher BMI reduction at 1 year, and no glucose-lowering drugs at baseline.

Practitioners should consider these factors when assessing remission potential.

Most of the reviewed studies indicated favorable effects of a vegetarian diet on oxidative status compared to omnivores.

Vegetarian diets may improve oxidative health markers.

The only inflammatory biomarker that seems to be associated with the vegetarian diet was inflammatory mediator C-reactive protein, which in several studies showed lower values in vegetarians as compared to omnivores.

Monitoring C-reactive protein levels may be beneficial for vegetarians.

New medications for T2DM, such as semaglutide, tirzepatide, and ertugliflozin, have been recently approved.

Healthcare providers should stay informed about newly approved medications for T2DM management.

High fructose diets have lipogenic effects.

Consider the implications of high fructose consumption on lipogenesis in dietary recommendations.

Managing cardiovascular, renal, and metabolic diseases holistically can lead to improved patient outcomes.

Practitioners should consider integrated care approaches to enhance patient outcomes.

Interdisciplinary team-based care models improve clinical outcomes for patients with cardiovascular, renal, and metabolic diseases.

Healthcare systems should implement interdisciplinary care models to enhance efficiency and patient outcomes.

Continuous glucose monitoring can be used to detect early dysglycemia in individuals with elevated glucose levels.

Practitioners can integrate continuous glucose monitoring into clinical practice to identify prediabetes.

Early detection of dysglycemia can be integrated into clinical practice settings.

Clinicians can adopt continuous glucose monitoring to enhance early detection of dysglycemia.

Person-generated health data (PGHD) provides a great opportunity for health management and care.

Practitioners should consider integrating PGHD into health management strategies.

Recommendations for enhancing PGHD and mHealth include integrating behavior change theory and technology adoption.

Practitioners should consider these recommendations to enhance the effectiveness of PGHD and mHealth.

Yoga intervention for 10 weeks significantly reduced DNA damage indicators in T2D subjects, including Tail Moment (-5.88; P = .013) and Olive Tail Moment (-2.93; P < .01).

Yoga may be an effective intervention for reducing DNA damage in individuals with type 2 diabetes.

Gastroenterologists can play an important role in the management of obesity.

Gastroenterologists should be prepared to manage obesity in their patients.

Weight management is a complex concept that requires multifaceted strategies for successful programs.

Practitioners should implement diverse strategies in weight management programs.

Unsuccessful weight management can lead to metabolic disorders and increased risk of mortality.

Highlight the importance of effective weight management to prevent serious health issues.