Research
Molecular
Higher ultraprocessed grain intake is associated with increased risk of developing inflammatory bowel disease (IBD), with participants consuming ≥19 g/d having a hazard ratio (HR) of 1.86 compared to those consuming <9 g/d.
Practitioners should advise minimizing ultraprocessed grain consumption to reduce IBD risk.
StrongSupportsmedium confidence
Participants consuming ≥19 g/d of ultraprocessed grains had a higher risk of developing IBD compared with those consuming <9 g/d (hazard ratio [HR] 1.86, 95% confidence interval 1.26-2.61, Ptrend = 0.0003) after multivariate adjustment.
Why this rating
Based on the large cohort size and prospective nature of the study.
Source
Ultraprocessed Grains and Risk of Inflammatory Bowel Disease: Results From the Prospective Urban Rural Epidemiology Study
Neeraj Narula et al. · The American Journal of Gastroenterology · 2025
cohort · n=124590Cited 3×
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