Research
Energy balance
Obese gut microbial communities exhibit higher branched-chain amino acid (BCAA) catabolism and hexanoic acid production, which may negatively impact energy balance and metabolic health.
Obese gut bacteria may metabolize proteins differently, producing metabolites like hexanoic acid that could affect energy balance. This highlights why metabolic health in obesity is complex and not just about calorie intake.
ModerateQualifiesMEDIUM confidence
We found that the obese microbial community had higher branched-chain amino acid catabolism and hexanoic acid production, potentially impacting energy balance.
Why this rating
In vitro metabolomics data; supports mechanism but requires in vivo validation.
Source
Tailored impact of dietary fibers on gut microbiota: a multi-omics comparison on the lean and obese microbial communities
Andrea Dell’Olio et al. · Microbiome · 2024
DOI 10.1186/s40168-024-01975-x
mechanism_only · n=6Cited 29×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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