Research
Metabolic adaptation
HEC-CG115 led to more weight loss than semaglutide in diet-induced obese model mice.
HEC-CG115 may be a more effective option for weight loss in obese patients compared to semaglutide.
StrongSupportsmedium confidence
HEC-CG115 (3 nmol/kg) led to more weight loss than semaglutide at a higher dose (10 nmol/kg) in diet-induced obese model mice.
Why this rating
Based on the comparison of effects in animal models.
Source
Development of a novel <scp>Fc</scp> fusion protein dual glucagon‐like peptide‐1 and gastric inhibitory polypeptide receptor agonists
Peng Jiang et al. · Diabetes Obesity and Metabolism · 2023
otherCited 3×
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