Research

Metabolic adaptation

Overfeeding reduced insulin sensitivity more in individuals with short sleep duration compared to those with longer sleep duration.

Encouraging adequate sleep may mitigate negative effects on insulin sensitivity during overeating.

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Overfeeding mediated weight gain reduced liver, adipose, and whole-body insulin sensitivity prominently in individuals with short sleep duration but not in individuals with longer sleep duration.
Prachi Singh et al. · The Journal of Clinical Endocrinology & Metabolism · 2024

Why this rating

Based on the longitudinal study design with healthy participants.

Source

Sleep Duration Alters Overfeeding-mediated Reduction in Insulin Sensitivity

Prachi Singh et al. · The Journal of Clinical Endocrinology & Metabolism · 2024

other · n=28Cited 2×
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