Research
Hormonal
Semaglutide initiated 6 months post LSG results in significantly greater absolute weight loss of 14.03 ± 5.26 kg compared to 5.63 ± 6.25 kg in controls from 6 to 12 months post LSG (p < 0.0001).
Practitioners may consider semaglutide as an effective adjunct therapy for weight management in patients post-sleeve gastrectomy.
StrongSupportsmedium confidence
From 6 to 12 months, the treatment group experienced significantly greater absolute (14.03 ± 5.26 kg vs. 5.63 ± 6.25 kg; p < 0.0001) weight loss than controls.
Why this rating
The study design is a retrospective analysis with matched controls, indicating strong evidence.
Source
Short‐Term Weight Loss Outcomes of 1.0 <scp>mg</scp> Semaglutide Therapy Initiated 6 Months After Sleeve Gastrectomy
Min He et al. · Obesity · 2025
DOI 10.1002/oby.70006
cohort · n=136Cited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Semaglutide therapy leads to a higher percentage weight loss of 12.61% ± 4.11% compared to 4.84% ± 5.18% in controls from 6 to 12 months post LSG (p < 0.0001).Strong
- At 12 months, total weight loss was higher in the treatment group (35.77% ± 8.35%) compared to controls (28.37% ± 7.41%; p < 0.0001).Strong
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