Research

Hormonal

The efficacy of GLP-1 receptor agonists was consistent across other important subpopulations.

GLP-1 receptor agonists can be considered effective for weight loss across diverse patient groups.

StrongSupportsmedium confidence
However, their efficacy was consistent across other important subpopulations.
G. Caleb Alexander et al. · JAMA Internal Medicine · 2026

Why this rating

Based on meta-analysis of multiple RCTs.

Source

Heterogeneity of Treatment Effects of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss in Adults

G. Caleb Alexander et al. · JAMA Internal Medicine · 2026

DOI 10.1001/jamainternmed.2025.8222

Meta-analysisCited 2×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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