Research
Metabolic adaptation
Heart failure with preserved ejection fraction (HFpEF) exacerbates the severity of metabolic dysfunction-associated steatotic liver disease (MASLD).
Healthcare providers should be aware that HFpEF can worsen MASLD, necessitating comprehensive management strategies.
StrongSupportsmedium confidence
Conversely, HFpEF exacerbates the severity of MASLD.
Why this rating
The abstract discusses established relationships and implications based on clinical observations.
Source
Metabolic Dysfunction-Associated Steatotic Liver Disease and Heart Failure with Preserved Ejection Fraction: A Bidirectional Relationship with Clinical and Therapeutic Implications
Ana Rita Leite et al. · Endocrinology Insights · 2024
DOI 10.1159/000541442
reviewCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Metabolic dysfunction-associated steatotic liver disease (MASLD) is an independent risk factor for diastolic dysfunction and heart failure with preserved ejection fraction (HFpEF), increasing the risk of hospitalization and death in those with established heart failure.Strong
- Lifestyle interventions, such as adherence to a Mediterranean diet and weight loss, have proven beneficial for both metabolic dysfunction-associated steatotic liver disease (MASLD) and heart failure with preserved ejection fraction (HFpEF).Strong
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