Macro partitioning
Total protein intake has a U-shaped association with diabetes risk, where both very low (<10.6% of energy) and very high (≥14.0% of energy) intakes are associated with higher risk compared to moderate intake (10.6-14.0% of energy).
Avoid both very low and very high total protein intakes. The study suggests that getting 10.6% to 14.0% of your daily calories from protein is associated with the lowest risk of developing diabetes. This means you should neither severely restrict protein nor consume excessive amounts, but rather aim for a moderate level.
Overall, there was a U-shaped association between the percentage energy from dietary total protein intake and new-onset diabetes... significantly higher risks of new-onset diabetes were found in participants in the first quintile (<10.6% of energy from total protein... and the fifth quintile (≥14.0% of energy...)
Why this rating
Large-scale prospective cohort with rigorous statistical modeling (restricted cubic splines).
Source
Variety and quantity of dietary protein intake from different sources and risk of new-onset diabetes: a Nationwide Cohort Study in China
Chun Zhou et al. · BMC Medicine · 2022
DOI 10.1186/s12916-021-02199-8
More from this paper
- A higher variety score of dietary protein sources (consuming appropriate quantities from more of the eight major sources: grains, meat, poultry, fish, egg, legumes) is inversely associated with the risk of new-onset diabetes.Good
- Specific protein sources have non-linear associations with diabetes risk: fish and legumes show inverse J/L-shaped associations (lower risk with higher intake), while red meat and poultry show J/U-shaped associations (increased risk at high intakes).Good
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
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